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Insulin is a hormone made by the pancreas that allows your body to use sugar (glucose) from carbohydrates in the food that you eat for energy or to store glucose for future use. Insulin helps keeps your blood sugar level from getting too high (hyperglycemia) or too low (hypoglycemia).

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Various types of insulin are used to treat diabetes and include:

Rapid-acting insulin: It starts working approximately 15 minutes after injection and peaks at approximately 1 hour but continues to work for two to four hours. This is usually taken before a meal and in addition to a long-acting insulin.

Short-acting insulin: It starts working approximately 30 minutes after injection and peaks at approximately 2 to 3 hours but will continue to work for three to six hours. It is usually given before a meal and in addition to a long-acting insulin.

Intermediate-acting insulin: It starts working approximately 2 to 4 hours after injection and peaks approximately 4 to 12 hours later and continues to work for 12-18 hours. It is usually taken twice a day and in addition to a rapid- or short-acting insulin. 

Long-acting insulin: It starts working after several hours after injection and works for approximately 24 hours. If necessary, it is often used in combination with rapid- or short-acting insulin.

Insulin can be given by a syringe, injection pen, or an insulin pump that delivers a continuous flow of insulin.

Many people get insulin into their blood using a needle and syringe, a cartridge system, or pre-filled pen systems.

The place on the body where you give yourself the shot may matter. You’ll absorb insulin the most consistently when you inject it into your belly. The next best places to inject it are your arms, thighs, and buttocks. Make it a habit to inject insulin at the same general area of your body, but change up the exact injection spot. This helps lessen scarring under the skin.

Inhaled insulin, insulin pumps, and a quick-acting insulin device are also available.

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It will depend on the type of insulin you use. You want to time your shot so that the glucose from your food gets into your system at about the same time that the insulin starts to work. This will help your body use the glucose and avoid low blood sugar reactions.

For example, if you use a rapid-acting insulin, you’d likely take it 10 minutes before or even with your meal. If you use regular- or intermediate-acting insulin, you should generally take it about a half-hour before your meals, or at bedtime. Follow your doctor’s advice.

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